BBP is a selective inhibitor of BVDV and CSFV replication.
Resistant viruses carry mutation I261M for BVDV or I261N/P262A for CSFV in the RdRp.
BBP-resistant pestiviruses show cross-resistant to known pestivirus inhibitors.
Inactive in an in vitro BVDV RdRp assay.
BBP does inhibit the activity of BVDV replication complexes.