Numerical prediction of peri-implant bone adaptation: Comparison of mechanical stimuli and sensitivity to modeling parameters
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- 作者：Marco Piccininia ; marco.piccinini@epfl.ch" class="auth_mail" title="E-mail the corresponding author ; Joel Cugnonia ; joel.cugnoni@epfl.ch" class="auth_mail" title="E-mail the corresponding author ; John Botsisa ; john.botsis@epfl.ch" class="auth_mail" title="E-mail the corresponding author ; Patrick Ammannb ; Patrick.Ammann@hcuge.ch" class="auth_mail" title="E-mail the corresponding author ; Anselm Wiskottc ; Anselm.Wiskott@unige.ch" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bone adaptation ; Implants integration ; Overloading ; Specimen-specific ; Finite element ; Gait ; Mechanical stimulus
- 刊名：Medical Engineering & Physics
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：38
- 期：11
- 页码：1348-1359
- 全文大小：3896 K
文摘
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Multiple formulations of bone adaptation models are compared on the case of implanted rat tibiae with external activation.
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Bone adaptation threshold is determined through a histogram analysis of the stimulus in physiological homeostatic conditions.
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The strain based stimulus was shown the most appropriate to implement a robust adaptation model at the continuum scale.
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The use of a ‘zone of influence’ filter larger that 3–5 trabecular spaces was found mandatory to obtain reliable results.
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Other modeling parameters were found to have a limited influence and their influence is discussed.