The Impact of Structural Heterogeneity on Excitation-Inhibition Balance in Cortical Networks

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• 作者：Itamar D. Landau¹ ; ² ; Robert Egger² ; ³ ; Vincent J. Dercksen² ; ⁴ ; Marcel Oberlaender² ; ³ ; ⁵ ; Haim Sompolinsky¹ ; ² ; ⁶ ; ⁷ ; ^{haim@fiz.huji.ac.il}
• 关键词：cortical networks ; dynamics ; balance ; adaptation ; inhibition ; homeostatic plasticity
• 刊名：Neuron
• 出版年：2016
• 出版时间：7 December 2016
• 年：2016
• 卷：92
• 期：5
• 页码：1106-1121
• 全文大小：3487 K
• 卷排序：92

文摘

Structural heterogeneity threatens the dynamic balance of excitation and inhibition Reconstruction of cortical networks reveals significant structural heterogeneity Spike-frequency adaptation can act locally to facilitate global balance Inhibitory homeostatic plasticity can compensate for structural imbalance