文摘
15 different PDE10A transcripts are now cataloged in the human brain The novel PDE10A transcripts have unique 5′ sequences but retain identical sequences in the carboxyl-half of the protein Novel PDE10A exons are conserved in non-human primate species and are rarely found in other mammals 108 “intronic” SNPs, of which 78% are rare variants, were found in the novel PDE10A exons, most residing in the 5’UTRs