Results of Deep Anterior Lamellar Keratoplasty for Advanced Keratoconus in Children Less Than 18 Years

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• 作者：Ritu AroraAuthor Vitae ; Pooja Jain ; ^{drpoojajain1@gmail.com" class="auth_mail" title="E-mail the corresponding author}Author Vitae ; Parul Jain ; Aditi Manudhane ; JawaharLal Goyal
• 刊名：American Journal of Ophthalmology
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：162
• 期：Complete
• 页码：191-198.e2
• 全文大小：1368 K

文摘

To evaluate the outcomes of deep anterior lamellar keratoplasty (DALK) in children with advanced keratoconus.

Design

Retrospective noncomparative interventional case series.

Methods

A retrospective analysis was conducted of 20 eyes of 16 patients who underwent deep anterior lamellar keratoplasty at a tertiary eye care center for advanced keratoconus. The main preoperative parameters measured were decimal uncorrected visual acuity (UCVA), decimal best-corrected visual acuity (BCVA), and average keratometry. The average keratometry was taken as an average of the flat and steep keratometric readings. The follow-up ranged from 24 to 105 months. The main outcome measures were UCVA, BCVA, steep and flat simulated keratometry, refraction, graft clarity, and complications.

Results

At the final follow-up, 18 patients had clear grafts in the visual axis area. Mean decimal UCVA changed from 0.06 ± 0.08 to 0.24 ± 0.09. Mean decimal BCVA changed from 0.12 ± 0.19 to 0.45 ± 0.24. The average keratometry decreased from 64.15 diopter (D) to 45.7 D after surgery. The complications noted in the patients were graft rejection (1), shield ulcers (2), graft infection (2), and interface vascularization (4). They were managed accordingly and only 1 patient needed penetrating keratoplasty.

Conclusions

DALK is an effective therapeutic modality for the management of advanced keratoconus in children.