刊名:Biochimica et Biophysica Acta (BBA) - Bioenergetics
出版年:2017
出版时间:January 2017
年:2017
卷:1858
期:1
页码:34-44
全文大小:1122 K
卷排序:1858
文摘
ATP-Dependent H+-pumping by E. coli ATP synthase depends on bound ADP and Pi. ε Subunit C-terminal domain truncation (εCTD ➔ εtr) reduced H+-pumping. ATP synthase-εtr maintained ATP hydrolytic activity; coupling was defective. Addition of ADP + Pi to ATP synthase-εtr stimulated ATP-dependent H+-pumping. It is proposed that εCTD modulates the binding of ADP and Pi to regulate coupling.