Drugs indicated for mitochondrial dysfunction as treatments for acute encephalopathy with onset of febrile convulsive status epileptics
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- 作者：Taku Omataa ; takuoma@hotmail.co.jp" class="auth_mail" title="E-mail the corresponding author ; Katsunori Fujiib ; Jun-ichi Takanashic ; Kei Murayamad ; Masaki Takayanagid ; Kaori Mutaa ; Kazuo Kodamaa ; Yukiko Iidaa ; Yoshimi Watanabea ; Naoki Shimojob
- 关键词：AESD ; acute encephalopathy with biphasic seizures and late reduced diffusion ; ANE ; acute necrotizing encephalopathy ; CPTII ; Carnitine palmitoyl transferase II
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：360
- 期：Complete
- 页码：57-60
- 全文大小：275 K
文摘
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Acute encephalopathy with onset of febrile convulsive status has severe sequelae.
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We studied the efficacy of a mitochondrial drug cocktail for encephalopathy.
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We used vitamins B1, C, and E, biotin, coenzyme Q10, and l-carnitine for cocktail.
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Sequelae were significantly better when cocktail was administered within 24 h.
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Early treatment with a mitochondrial drug cocktail may improve prognosis.