Activated microglia in acute encephalopathy with biphasic seizures and late reduced diffusion
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- 作者：Yuji Fujitaa ; ojifujita@hotmail.co.jp" class="auth_mail" title="E-mail the corresponding author ; Jun-ichi Takanashib ; Haruka Takeia ; Setsuo Otaa ; Katsunori Fujiic ; Hiroshi Sakumad ; Masaharu Hayashid
- 关键词：AD ; Alzheimer's disease ; AESD ; acute encephalopathy with biphasic seizures and late reduced diffusion ; ALS ; amyotrophic lateral sclerosis ; GFAP ; glial fibrillary acidic protein ; HE ; hematoxylin-eosin ; MRS ; magnetic resonance spectroscopy
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：366
- 期：Complete
- 页码：91-93
- 全文大小：539 K
文摘
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We firstly performed a brain biopsy in a patient with AESD.
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Pathological findings revealed activated amoeboid microglia accumulation.
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Glutamate released from activated microglia may play an important role in AESD.
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It is compatible with the previous report of MRS showing elevated glutamate.