Comparison of mineral trioxide aggregate and calcium hydroxide for apexification of immature permanent teeth: A systematic review and meta-analysis

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• 作者：Jia-Cheng Lin ; Jia-Xuan Lu ; Qian Zeng ; Wei Zhao ; Wen-Qing Li ; Jun-Qi Ling ; ^{lingjq@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
• 关键词：apexification ; calcium hydroxide ; immature teeth ; mineral trioxide aggregate
• 刊名：Journal of the Formosan Medical Association
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：115
• 期：7
• 页码：523-530
• 全文大小：1318 K

文摘

Calcium hydroxide and mineral trioxide aggregate (MTA) are used for inducing a calcific barrier at an open tooth root (apexification). The purpose of this study was to compare the efficacy of calcium hydroxide and MTA for apexification of immature permanent teeth.

Methods

Medline, Cochrane, EMBASE, and Google Scholar were searched until November 24, 2015, using the keywords apexification, permanent teeth, MTA, and calcium hydroxide.

Results

Of 216 studies identified, four studies were included. There were no differences in the clinical success rate [pooled odds ratio (OR) = 3.03, 95% confidence interval (CI): 0.42–21.72, p = 0.271], radiographic success rate (pooled OR = 4.30, 95% CI: 0.45–41.36, p = 0.206), or apical barrier formation rate (pooled OR = 1.71, 95% CI: 0.59–4.96, p = 0.322) between calcium hydroxide and MTA groups. The time required for apical barrier formation was significantly less in the MTA group (pooled difference in means = −3.58, 95% CI: from −4.91 to −2.25, p < 0.001).

Conclusion

While both materials provide similar success rates, the shorter treatment time with MTA may translate into higher overall success rates because of better patient compliance.