刊名:International Journal of Biological Macromolecules
出版年:2017
出版时间:February 2017
年:2017
卷:95
期:Complete
页码:281-287
全文大小:1792 K
卷排序:95
文摘
β-ecdysone strongly binds to the active site and thereby inhibiting BACE1 activity. β-ecdysone binding induces open to closed conformational transition of BACE1. β-ecdysone also is a strong Aβ aggregation inhibitor, confirmed by AFM study.