Detection of Helicobacter pylori and the genotypes of resistance to clarithromycin and the heterogeneous genotype to this antibiotic in biopsies obtained from symptomatic children

详细信息    查看全文

• 作者：John Jairo Aguilera-Correa^a ; ^b ; Pedro Urruzuno^c ; Josefa Barrio^d ; Marí ; a José ; Martinez^e ; Sonia Agudo^a ; Angela Somodevilla^a ; Laura Llorca^a ; Teresa Alarcó ; n^a ; ^b ; ^{talarcon@helicobacterspain.com}
• 关键词：Heterogeneous genotypes ; Clarithromycin resistance ; Pediatric patients
• 刊名：Diagnostic Microbiology and Infectious Disease
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：87
• 期：2
• 页码：150-153
• 全文大小：334 K
• 卷排序：87

文摘

81.6% of biopsies from symptomatic children were H. pylori positive by PCR. Clarithromycin genotype: 42.3% wild-type, 47.7% resistant and 9.9% heterogeneous. Mutations detected: A2143G (87.5%), A2142G (7.5%) and double A2142C-A2143G (5%) Heterogeneous genotypes showed wild-type genotype plus mutation, A2143G or A2142G