- 作者：Zhijuan Pan1 ; Xiaoni Yuan1 ; Yang Li1 ; Xiaojin Wu2 ; Wenjuan Zhu2 ; Xiaojin Bao1 ; Qinqin Zhao2 ; Jun He1 ; junhe1964@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Anti-HLA antibodies ; HLA-DP ; Acute graft-versus-host disease (aGVHD) ; Unrelated donor ; Hematopoietic stem cell transplantation (HSCT) ; Outcomes
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：22
- 期：1
- 页码：86-95
- 全文大小：838 K
- 1.
Dynamic detection of anti-HLA antibodies can predict graft-versus-host disease and overall survival in HLA 12/12–matched unrelated donor hematopoietic stem cell transplantation for hematological malignancies, especially for acute myeloid leukemia/myelodysplastic syndromes
- 2.
Routine monitoring for anti-HLA antibody dynamics should be conducted before and after hematopoietic stem cell transplantation
- 3.
Anti-HLA antibodies independently predicted for negative outcome of hematopoietic stem cell transplantation independent of HLA-DP loci mismatches. HLA-DP loci mismatches were associated with poor prognosis in the anti-HLA Abs-negative group
- 4.
For the first time, we reported the impact of anti-HLA antibodies and HLA-DP loci mismatches on hematopoietic stem cell transplantation outcomes in HLA 12/12–matched unrelated donor hematopoietic stem cell transplantation