A new library of 4(3H)- and 4,4¡ä(3H,3H¡ä)-quinazolinones and 2-(5-alkyl-1,2,4-oxadiazol-3-yl)quinazolin-4(3H)-one obtained from diaminoglyoxime
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- 作者：Abolghasem Moghimi ; Rahim Hosseinzadeh Khanmiri ; Ismail Omrani ; Ahmad Shaabani
- 关键词：Quinazolinone ; Diaminoglyoxime ; Anthranilic acid ; 1 ; 2 ; 4-Oxadiazole ; Condensation
- 刊名：Tetrahedron Letters
- 出版年：2013
- 出版时间：24 July, 2013
- 年：2013
- 卷：54
- 期：30
- 页码：3956-3959
- 全文大小：1358 K
文摘
New and efficient approaches are developed for the synthesis of a series of 4(3H)- and 4,4¡ä(3H,3H¡ä)-quinazolinone derivatives and 2-(5-alkyl-1,2,4-oxadiazol-3-yl)quinazolin-4(3H)-one in good yields, via the reactions of diaminoglyoxime and anthranilic acid derivatives or methyl 2-aminobenzoate and acetic anhydride in acetic acid as the solvent under reflux conditions.