Oral administration of Nigella sativa oil ameliorates the effect of cisplatin on membrane enzymes, carbohydrate metabolism and oxidative damage in rat liver

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• 作者：Zeba Farooqui^a ; Mohammad Afsar^a ; Sana Rizwan^a ; Aijaz Ahmed Khan^b ; Farah Khan^a ; ^{dr.farahkhan23@gmail.com}
• 关键词：ACPase ; acid phosphatase ; ALP ; alkaline phosphatise ; ALT ; alanine aminotransferase ; AST ; aspartate aminotransferases ; BUN ; blood urea nitrogen ; BBM ; brush border membrane ; BBMV ; BBM vesicles ; Scr ; serum creatinine ; CAT ; catalase ; CP ; cisplatin ; Chl ; cholesterol ; FBPase ; fructose 1 ; 6 ; G6Pase ; glucose 6-phosphatase ; G6PDH ; glucose 6-phosphate dehydrogenase ; GGTase ; γ-glutamyl transferase ; Glc ; glucose ; GR ; glutathione reductase ; GSH ; glutathione ; GSHPx ; glutathione peroxidise ; GST ; glutathione S-t
• 刊名：Toxicology Reports
• 出版年：2016
• 出版时间：2016
• 年：2016
• 卷：3
• 期：Complete
• 页码：328-335
• 全文大小：1038 K
• 卷排序：3

文摘

NSO improves the endogenous antioxidant status and metabolic activity of liver. NSO protects the liver against CP generated free radical attack. Oral administration of NSO ameliorates the hepatotoxicity induced by CP treatment.