Resequencing diverse Chinese indigenous breeds to enrich the map of genomic variations in swine
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- 作者：Huimin Kanga ; 1 ; nongdaxiaokang@126.com" class="auth_mail" title="E-mail the corresponding author ; Haifei Wanga ; 1 ; wanghaiffei@126.com" class="auth_mail" title="E-mail the corresponding author ; Ziyao Fana ; 1 ; nuclearfan@cau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Pengju Zhaoa ; zhaopengju2014@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Amjad Khana ; amjadkhanqau@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Zongjun Yinb ; yinzongjun@ahau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jiafu Wangc ; jfwang@gzu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Wenbin Baod ; wbbbao@yzu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Aiguo Wanga ; agwang@cau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Qin Zhanga ; qzhang@cau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jian-Feng Liua ; liujf@cau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：SNVs ; single nucleotide variants ; INDELs ; short insertions & deletions ; NGS ; next-generation sequencing ; SNPs ; single nucleotide polymorphisms ; Sus scrofa ; S. scrofa ; dbSNP ; Database of Short Genetic Variation ; GWAS ; genome-wide association study ; GS ; genomic selection ; QUAL ; quality score ; GO ; Gene Ontology ; CDS ; coding sequences ; UTRs ; untranslated regions ; ncRNA ; non-coding RNA ; refGene ; RefSeq Genes ; OMIM ; Online Mendelian Inheritance in Man ; OMIA ; Online Mendelian Inheritance in Animals ; FP
- 刊名：Genomics
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：106
- 期：5
- 页码：286-294
- 全文大小：615 K
文摘
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2,530,248 SNVs and 3,456,626 INDELs were firstly discovered compared with dbSNP 143.
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208,687 SNVs and 24,161 INDELs were uniquely observed in Chinese pigs.
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Significantly high correlation between SNV and INDEL was detected.
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LoF genes were found to be under weaker evolutionary constraints.