Effect of DSPE-PEG on compound action potential, injury potential and ion concentration following compression in ex vivo spinal cord
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- 作者：Aihua Wanga ; b ; Xiaolin Huoa ; huoxl@mail.iee.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Guanghao Zhanga ; Xiaochen Wanga ; b ; Cheng Zhanga ; Changzhe Wua ; Wei Rongc ; Jing Xud ; Tao Songa
- 关键词：Spinal cord injury ; Membrane sealing ; Compound action potential ; Injury potential ; Ion influx ; Double sucrose gap technique
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：4 May 2016
- 年：2016
- 卷：620
- 期：Complete
- 页码：50-56
- 全文大小：1373 K
文摘
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Gap potential variance after injury describe ex vivo injury potential.
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DSPE-PEG restore CAP at a much lower concentration than PEG.
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Application of DSPE-PEG after SCI hardly change intracellular ions concentration.
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The CAP restoring effect of DSPE-PEG relies on membrane resealing.