An unprecedented dual responsive gelation of Carbopol induced by Pluronic P123 triblock copolymer
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文摘

P123 induces unprecedented gelation of Carbopol in presence of salt below its pKa.

Carbopol-P123 hydrogel exhibited dual responsivity.

Gelation of hydrogel is tunable by altering polymer concentration, pH temperature.

Naproxen release from hydrogel is pH dependent and occurs without burst release.

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