Genetic alteration regulated by microRNAs in biliary tract cancers
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- 作者：Ning Wang ; Shihai Xia ; Kai Chen ; Xiaohui Xiang ; xiaohuixiang@163.com" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Aijun Zhu ; zhaj_1023@163.com" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：BTC ; biliary tract cancer ; CC ; cholangiocarcinoma ; ECC ; extra-hepatic cholangiocarcinoma ; EMT ; epithelial to mesenchymal transition ; ERCP ; endoscopic retrograde cholangiopancreatography ; GBC ; gallbladder carcinoma ; ICC ; intra-hepatic cholangiocarcinoma ; IL-6 ; Interleukin-6 ; PSC ; primary sclerosing cholangitis ; PTC ; percutaneous transhepatic cholangiography ; SNPs ; single nucleotide polymorphisms ; UTR ; untranslated region
- 刊名：Critical Reviews in Oncology and Hematology
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：96
- 期：2
- 页码：262-273
- 全文大小：943 K
文摘
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We sum up the relationship between miRNAs and BTCs on potential genetic alteration.
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This review enlightens us the targets regulated by miRNAs in BTCs.
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The expression changes and roles of different miRNAs in BTCs were elaborated.
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Clinical applications of miRNAs might include biomarkers and therapeutic targets.