Efficient acetone-butanol-ethanol (ABE) production by a butanol-tolerant mutant of Clostridium beijerinckii in a fermentation-pervaporation coupled process
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- 作者：Xiangping Kong ; Aiyong He ; Jie Zhao ; Hao Wu ; Jiangfeng Ma ; majiangfeng@njtech.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Ce Wei ; Wanqin Jin ; Min Jiang ; bioengine@njtech.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Biosynthesis ; Butanol tolerance ; Atmospheric and room-temperature plasmas ; Fed-batch culture ; Pervaporation ; Process integration
- 刊名：Biochemical Engineering Journal
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：105
- 期：part_PA
- 页码：90-96
- 全文大小：991 K
文摘
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Mutants with high butanol tolerance were obtained by ARTP mutagenesis.
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Enhanced ABE production of 18.8 g/L was achieved during batch fermentation.
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Butanol-tolerant mutant was first applied to PV coupled ABE fermentation.
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ABE productivity was significantly improved by using BT14 and pervaporation.