p75 Neurotrophin Receptor Regulates Energy Balance in Obesity
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- 作者：Bernat Baeza-Raja1 ; Benjamin D. Sachs2 ; Pingping Li3 ; Frank Christian4 ; Eirini Vagena1 ; Dimitrios Davalos1 ; Natacha Le Moan1 ; Jae Kyu Ryu1 ; Shoana L. Sikorski2 ; Justin P. Chan1 ; Miriam Scadeng5 ; Susan S. Taylor2 ; 6 ; Miles D. Houslay7 ; George S. Baillie4 ; Alan R. Saltiel3 ; Jerrold M. Olefsky3 ; Katerina Akassoglou1 ; 8 ; kakassoglou@gladstone.ucsf.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：12 January 2016
- 年：2016
- 卷：14
- 期：2
- 页码：255-268
- 全文大小：3838 K
文摘
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p75NTR-null mice are protected from diet-induced obesity
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p75NTR regulates energy expenditure and fat oxidation
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p75NTR inhibits the dissociation of the PKA holoenzyme and suppresses cAMP
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Adipocyte-specific p75NTR knockout protects mice from diet-induced obesity