TLR7 Structure: Cut in Z-Loop

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• 作者：Kazuhiko Maeda¹ ; ² ; Shizuo Akira¹ ; ² ; ^{sakira@biken.osaka-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Immunity
• 出版年：2016
• 出版时间：18 October 2016
• 年：2016
• 卷：45
• 期：4
• 页码：705-707
• 全文大小：480 K

文摘

TLRs play central roles in host defense. In this issue of Immunity, Zhang et al. (2016) generate structures of TLR7 bound to multiple ligands and provide insight into the mechanism of TLR7 ligand recognition that highlights the differences in the features of the TLR subfamily.