- 作者：Demet Alaygut ; Alper Soylu ; Belde Kasap ; Mehmet T¨¹rkmen ; H ; an ?akmakc? ; Salih Kavukcu
- 刊名：Urology
- 出版年：2013
- 出版时间：August, 2013
- 年：2013
- 卷：82
- 期：2
- 页码：442-447
- 全文大小：91 K
Objective
To evaluate the factors associated with compensatory hypertrophy in the functional kidneys of children.Methods
The medical files of patients with a solitary functional kidney were reviewed retrospectively. Data regarding anthropometric measurements, functional renal length, functional renal length of standard deviation score (SDS) of functional kidney at diagnosis, and end of follow-up were obtained. Patients were divided into 2 groups, those with a unilateral kidney function of?<10 % (hypoplasia, dysplasia, and atrophy, group 1) and those with a solitary kidney (agenesis, and multicystic dysplastic kidney, group 2).
Results
A total of 126 patients (70 boys) were evaluated. Both the sizes of the functional kidney and functional kidney SDS values at diagnosis were greater in group 1 relative to group 2. At the end of the follow-up period, anthropometric values including functional kidney size were higher in group 2. Functional kidney size of 2 SDS above the normal was mostly predictive at age 17.5?months (odds ratio [OR] 5.06) and at a body height of 82?cm (OR 5.57).
Conclusion
The most determining factors for renal length SDS values were age and height. Solitary kidneys complete compensatory hypertrophy by 17.5?months of age, and after that their growth continues in parallel to normal growth.