Ethnomedicinal uses of Momordica charantia (Cucurbitaceae) in Togo and relation to its phytochemistry and biological activity
详细信息 查看全文
- 作者：Beloin ; Nadine ; Gbeassor ; Messanvi ; Akpagana ; Koffi ; Hudson ; Jim ; de Soussa ; Komlan ; Koumaglo ; Kossi ; et. al.
- 关键词：Ethnobotany ; Momordica charantia ; Medicinal plant ; Traditional healers ; Antiviral ; Anthelmintic
- 刊名：Journal of Ethnopharmacology
- 出版年：2005
- 出版时间：January 4, 2005
- 年：2005
- 卷：96
- 期：1-2
- 页码：49-55
- 全文大小：98.2 K
文摘
Investigation of the traditional uses of Momordica charantia (Cucurbitaceae) in Togo (West Africa) showed that it is one of the most important local medicinal plants both for ritual and ethnomedical practices. There was a high degree of consensus (>50 % ) for use in the treatment of gastrointestinal and viral disease among 47 groups of village informants in the general population, while 19 traditional healers reported a larger and broader set of uses. The use by informants in Gaur and Kwa language groups was not significantly different. Lyophilized Momordica charantia extracts prepared from accessions collected in Togo showed high antiviral activity (<5 μg/ml) against Sindbis and Herpes simplex type 1 viruses and anthelmintic activity against Caenorhabditis elegans at 500 μg/ml. Presence in the leaves of the triterpene glycosides momordicins I and II follows biological activity of the plant extracts. However, momordicins were found to be anthelmintic but not antiviral. Traditional healers collected plants in dry areas where momordicin content is greater.