Molecular characterization and expression analysis of mitochondrial antiviral signaling protein gene in sea perch, Lateolabrax japonicus
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- 作者：Peng Jiaa ; b ; c ; jiapeng19890219@126.com" class="auth_mail" title="E-mail the corresponding author ; Yilin Jina ; b ; c ; 369277368@qq.com" class="auth_mail" title="E-mail the corresponding author ; Limin Chena ; b ; c ; 2562492896@qq.com" class="auth_mail" title="E-mail the corresponding author ; Jing Zhanga ; b ; c ; zhangj358@mail2.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Kuntong Jiaa ; b ; c ; jiakuntong@126.com" class="auth_mail" title="E-mail the corresponding author ; Meisheng Yia ; b ; c ; yimsh@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mitochondrial antiviral signaling protein ; Sea perch ; Nervous necrosis virus ; Innate immune
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：55
- 期：Complete
- 页码：188-193
- 全文大小：1758 K
文摘
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The first MAVS was identified from sea perch.
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LjMAVS transcripts were constitutively expressed in all examined tissues.
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LjMAVS transcripts were induced in immune and non-immune organs post NNV infection in vivo.
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LjMAVS involved in response to poly I:C stimulation and NNV infection.
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Over-expression of LjMAVS inhibited RGNNV replication significantly.