A novel coumarin based molecular switch for the sequential detection of Al³⁺ and F⁻: Application in lung cancer live cell imaging and construction of logic gate

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• 作者：Deblina Sarkar^aAuthor Vitae ; Paramita Ghosh^aAuthor Vitae ; Saswati Gharami^bAuthor Vitae ; Tapan Kumar Mondal^b ; ^{tkmondal@chemistry.jdvu.ac.in}Author Vitae ; Nabendu Murmu^a ; ^{nabendu.murmu@cnci.org.in} ; ^{nabendu64@gmail.com}Author Vitae
• 关键词：Coumarin based sequential chemosensor for Al3+ and F&minus ; Spectral characterization ; A549 lung cancer cell line ; Live cell imaging ; INHIBIT logic gate ; DFT calculation
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：April 2017
• 年：2017
• 卷：242
• 期：Complete
• 页码：338-346
• 全文大小：2379 K
• 卷排序：242

文摘

Development of novel coumarin based molecular switch for sequential detection of Al3+ and F−. UV–Vis and emission spectral changes confirms the sensing property of the developed chemosensor H2L. DFT used to get insight into the sensing mechanism and electronic structure of the chemosensor H2L. H2L is efficient in detecting Al3+ in the intracellular region of human lung cancer cell line A549. Exhibits an INHIBIT logic gate with Al3+ and F− as chemical inputs by monitoring the emission mode at 610 nm.