Body mass index and myocardium at risk in patients with acute coronary syndrome

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• 作者：A.L. Arrebola-Moreno^a ; ^b ; ^{alam_1981@hotmail.com" class="auth_mail} ; R. Marfil-Alvarez^c ; A. Catena^c ; R. Garcí ; a-Retamero^c ; J.P. Arrebola^c ; R. Melgares-Moreno^a ; J.A. Ramirez-Herná ; ndez^a ; J.C. Kaski^b
• 关键词：CAD ; coronary artery disease ; ACS ; acute coronary syndrome ; BMI ; body mass index ; PCI ; percutaneous coronary intervention ; BARIsc ; BARI score ; AMI ; acute myocardial infarction ; NSTEMI ; non-ST elevated myocardial infarction ; STEMI ; ST elevated myocardial infarction
• 刊名：Revista Cl铆nica Espa帽ola
• 出版年：April, 2014
• 年：2014
• 卷：214
• 期：3
• 页码：113-120
• 全文大小：1102 K

文摘

Background and objectives

Whilst traditional studies have shown that obese individuals are at a higher risk of cardiovascular events compared to lean subjects, recent studies in patients with acute myocardial infarction (AMI) have suggested that obesity may exert protective effects (the 鈥渙besity paradox鈥?. We sought to assess the relationship between body mass index (BMI) and the BARI score (BARIsc), a validated tool used to assess myocardium at risk, in patients with acute coronary syndrome.

Patients and methods

Participants were 116 consecutive patients (mean age, 60.6 years; 97 men) with AMI (68 ST elevated myocardial infarction, STEMI; 48 non-ST elevated myocardial infarction, NSTEMI). Demographics, BMI, risk factors, biochemistry data, left ventricular function, angiographic data and the BARIsc were assessed in every patient.

Results

Multiple linear regression analyses showed that BMI significantly correlated with BARIsc; 尾 = .23, p < 0.02. This was found only in the overweight/obese patients, 尾 = .27, p < 0.01, but not in patients with normal BMIs, 尾 = 0.08, p = 0.71.

Conclusions

An increased body weight is associated with an increased area of myocardium at risk in patients with ACS.