Associations between inflammatory cytokines and organ damage in pediatric patients with hemophagocytic lymphohistiocytosis
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- 作者：Shi-Long Yang1 ; Xiao-Jun Xu1 ; Yong-Min Tang ; Y_M_TANG@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Hua Song ; Wei-Qun Xu ; Fen-Ying Zhao ; Di-Ying Shen
- 关键词：HLH ; hemophagocytic lymphohistiocytosis ; ALT ; alanine aminotransferase ; AST ; asparate aminotransferase ; LDH ; lactate dehydrase ; IL ; interleukin ; TNF ; tumor necrosis factor ; IFN ; interferon ; EBV ; Epstein-Barr virus ; CBA ; cytometric bead array
- 刊名：Cytokine
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：85
- 期：Complete
- 页码：14-17
- 全文大小：382 K
文摘
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IL-6, IL-10 and IFN-γ are elevated in HLH.
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IFN-γ contributes to liver impairment and coagulation disease in HLH.
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IL-10 is a cytokine related to cytopenias in HLH.