A Molecular Titration System Coordinates Ribosomal Protein Gene Transcription with Ribosomal RNA Synthesis
详细信息 查看全文
- 作者：Benjamin Albert1 ; Britta Knight1 ; Jason Merwin1 ; Victoria Martin1 ; Diana Ottoz1 ; Yvonne Gloor1 ; Maria Jessica Bruzzone1 ; Adam Rudner2 ; 3 ; David Shore1 ; 4 ; david.shore@unige.ch" class="auth_mail" title="E-mail the corresponding author
- 关键词：transcription ; ribosomal protein gene ; ribosomal RNA ; Utp22 ; Ifh1 ; CURI complex ; Saccharomyces cerevisiae ; transcription factor titration
- 刊名：Molecular Cell
- 出版年：2016
- 出版时间：17 November 2016
- 年：2016
- 卷：64
- 期：4
- 页码：720-733
- 全文大小：2370 K
文摘
- •
Ifh1-Utp22 interaction coordinates RPG and rRNA transcription
- •
Sch9 regulates Ifh1 release at a short timescale after nutrient stress
- •
Utp22 is required for stable release of Ifh1 following TORC1 inhibition
- •
Utp22 couples RNAPI activity to RPG transcription independently of TORC1