Hematological particularities and co-infections in injected drug users with AIDS

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• 作者：Denise Menezes Brunetta ; Gil Cunha De Santis ; Fern ; o Crivelenti Vilar ; Renata Amorim Br ; 茫o ; Renata Zomer de Albernaz Muniz ; Geovana Momo Nogueira de Lima ; Manuela Emiliana Amorelli-Chacel ; Dimas Tadeu Covas ; Alcyone Artioli Machado
• 关键词：AIDS ; Injected drug use ; Anemia ; HCV ; Mycobacteria
• 刊名：The Brazilian Journal of Infectious Diseases
• 出版年：November-December, 2013
• 年：2013
• 卷：17
• 期：6
• 页码：654-656
• 全文大小：348 K

文摘

HIV patients infected through injected drug use have poorer prognosis than other groups. We evaluated the hematological alterations and rates of co-infections in injected drug use patients with AIDS. Injected drug use patients were younger, predominantly of male gender, and presented lower CD4, total lymphocyte, and platelet counts, but not neutrophil count, than control group. Injected drug use patients had a higher rate of hepatitis C and mycobacteria infection. Furthermore, all injected drug use patients with hemoglobin <10.0 g dL^鈭? and lymphocyte <1000 渭L^鈭? had CD4 count lower than 100 渭L^鈭?. In conclusion, HIV-infected injected drug use patients constitute a special group of patients, and hemoglobin concentration and lymphocyte count can be used as surrogate markers for disease severity.