- 作者：C. Noilhan ; M. Barigou ; med_barigou@yahoo.fr" class="auth_mail" title="E-mail the corresponding author ; L. Bieler ; J. Amar ; B. Chamontin ; B. Bouhanick
- 关键词：Young hypertension ; Causes ; Etiologies ; Systolic blood pressure ; Diastolic blood pressure ; Primary aldosteronism ; Secondary aldosteronism ; Essential hypertension
- 刊名：Annales de Cardiologie et d'Angeiologie
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：65
- 期：3
- 页码：159-164
- 全文大小：321 K
Methods
We conducted a retrospective overview of patients younger than 40 years old hospitalized consecutively in the Hypertension department of Toulouse University Hospital between 2012 and 2014. Clinical data about gender, age, anthropomorphic parameters and blood pressure measurement by 24 h Ambulatory Blood Pressure Monitoring (ABPM) were recorded. Biological data concerned dosages of kalemia, renin and aldosterone in the supine or after 15 min of seating. Recorded radiological examinations were renal artery ultrasound and abdominal CT scan.
Results
One hundred and forty-eight detailed medical records were analyzed, 69 women and 79 men. Among the 69 women, the causes of secondary hypertension were primary aldosteronism (n = 7), fibromuscular dysplasia (n = 5) and renal disease (n = 4). Oral contraceptives were involved in 13 women. In addition, essential hypertension concerned 40 women (58%). Among the 79 men, the causes of secondary hypertension were primary aldosteronism (n = 10), fibromuscular dysplasia (n = 3), left main renal artery entrapment by a diaphragmatic crura (n = 2), renal disease (n = 1), pheochromocytoma (n = 3) and coarctation of the aorta (n = 2). In addition, essential hypertension concerned 58 men (73%).
Conclusions
In our population, the prevalence of secondary hypertension is close to 33% (42% of females and 27% of males), with the following main causes: primary aldosteronism for 11.5%; fibromuscular dysplasia for 5.4%. Oral contraceptives were involved in the hypertension of 19% of the females.