Efficacy, safety, and acceptability of thermocoagulation for treatment of cervical intraepithelial neoplasia in a hospital setting in Brazil

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• 作者：Paulo S.V. Naud^a ; ^b ; Richard Muwonge^c ; Eduardo P. Passos^a ; ^b ; Valentino Magno^b ; Jean Matos^a ; Rengaswamy Sankaranarayanan^c ; ^{sankarr@iarc.fr" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Cervical intraepithelial neoplasia ; Thermocoagulation
• 刊名：International Journal of Gynecology and Obstetrics
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：133
• 期：3
• 页码：351-354
• 全文大小：166 K

文摘

To analyze the acceptability, safety, and effectiveness of thermocoagulation for the treatment of histologically proven cervical intraepithelial neoplasia grade 2–3 (CIN2–3) lesions.

Methods

In a retrospective study, data were obtained for women treated for CIN2–3 lesions by thermocoagulation at the Hospital de Clínicas de Porto Alegre, Brazil, between March 6, 2012, and October 29, 2013, and followed up after 1 year. The proportions of women with no evidence of disease, adverse effects, or complications were determined.

Results

Among 52 women included, 44 (85%) had no evidence of disease 1 year after thermocoagulation. The rate of no disease at follow-up was similar for women treated for CIN2 (17/20 [85%]) and CIN3 (27/32 [84%]). No serious adverse effects or complications requiring hospitalization were observed during the follow-up period.

Conclusion

Thermocoagulation is useful in the management of ectocervical CIN and should be integrated into public health services for management of cervical cancer.