Essential oil of Lindera neesiana fruit: Chemical analysis and its potential use in topical applications

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• 作者：Stefano Comai ; Stefano Dall'Acqua ; Alessia Grillo ; Ignazio Castagliuolo ; Khilendra Gurung ; Gabbriella Innocenti
• 关键词：Lindera neesiana ; Lauraceae ; Essential oil of fruit ; NMR ; GC-MS ; Antimicrobial activity
• 刊名：Fitoterapia
• 出版年：2010
• 出版时间：January 2010
• 年：2010
• 卷：81
• 期：1
• 页码：11-16
• 全文大小：309 K

文摘

The composition of the essential oil of Lindera neesiana Kurz fruit was examined by GC-MS, ¹H, ¹³C and bidimensional NMR techniques (HMQC, HMBC, COSY, TOCSY). Forty compounds were identified, representing approximately 86 % of the oil: Z-citral (15.08 % ), E-citral (11.89 % ), eucalyptol (8.75 % ), citronellal (6.72 % ), α-pinene (6.63 % ) and β-pinene (5.61 % ) were the major components. The essential oil of L. neesiana fruit showed significant antimicrobial activity against Staphylococcus aureus and Candida albicans at non-cytotoxic doses in human keratinocytes, suggesting possible topical applications.

Graphical abstract

The essential oil of Lindera neesiana was investigated by GC-MS and NMR techniques. Its biological activities suggest possible topical applications.