In ovo treatment with an estrogen receptor alpha selective agonist causes precocious development of the female reproductive tract of the American alligator (Alligator mississippiensis)
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- 作者：Brenna M. Doheny ; bdoheny@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Satomi Kohno ; Benjamin B. Parrott ; Louis J. Guillette Jr.
- 关键词：Alligator ; Oviduct ; Estrogen receptor ; IGF-1
- 刊名：General and Comparative Endocrinology
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：238
- 期：Complete
- 页码：96-104
- 全文大小：3056 K
文摘
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ERα agonist PPT induces hypertrophy of the embryonic alligator Müllerian duct.
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ERβ agonist WAY 200070 and 17-β estradiol do not induce this hypertrophy.
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PPT-treated Müllerian ducts display precocious glandular development.
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PPT alters Müllerian duct mRNA levels of steroid hormone receptors and IGF-1.