Botulinum neurotoxin type A alleviates mechanical hypersensitivity associated with infraorbital nerve constriction injury in rats

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• 作者：Noboru Noma^a ; ^{noma.noboru@nihon-u.ac.jp} ; Kosuke Watanabe^a ; Yuka Sato^a ; Yoshiki Imamura^a ; Yumiko Yamamoto^c ; Reio Ito^d ; Mitsuru Maruno^d ; Kohei Shimizu^e ; Koichi Iwata^b
• 关键词：BoNT-A ; ION-CCI ; Allodynia ; Hyperalgesia ; pERK
• 刊名：Neuroscience Letters
• 出版年：2017
• 出版时间：10 January 2017
• 年：2017
• 卷：637
• 期：Complete
• 页码：96-101
• 全文大小：1469 K
• 卷排序：637

文摘

BoNT-A alleviated ION-CCI-induced mechanical allodynia and hyperalgesia. High-dose BoNT-A suppressed nocifensive behavior. BoNT-A decreased Vc neuronal responses after noxious stimulation.