Outpatient Management of Stable Acute Pulmonary Embolism: Proposed Accelerated Pathway for Risk Stratification

详细信息    查看全文

• 作者：Amjad AlMahameed ; Teresa L. Carman
• 关键词：Anticoagulation ; Pharmacotherapy ; Pulmonary embolism ; Risk stratification ; Treatment ; Venous thromboembolism
• 刊名：The American Journal of Medicine
• 出版年：2007
• 出版时间：October 2007
• 年：2007
• 卷：120
• 期：10, Supplement 2
• 页码：S18-S25
• 全文大小：189 K

文摘

Pulmonary embolism (PE) is a major health problem and a cause of worldwide morbidity and mortality. The current standard therapy for acute PE encourages admitting patients to the hospital for administration of parenteral anticoagulation therapy as a bridge to oral vitamin K antagonists. Prognostic models that identify patients with stable (nonmassive) acute PE (SPE) who are at low risk for adverse outcome have recently been reported. Based on these risk stratification models, hospital-based therapy is warranted for patients with PE who meet the criteria associated with a high risk for adverse outcome. However, a growing body of evidence suggests the feasibility of partial outpatient management and accelerated hospital discharge (AHD) in a subset of patients with SPE. Prospective validation of these risk stratification models for predicting patient suitability for AHD is needed.