Further evidences for the mode of action of the larvicidal m-pentadecadienyl-phenol isolated from Myracrodruon urundeuva seeds against Aedes aegypti
详细信息 查看全文
- 作者：Terezinha M. Souzaa ; Erika S. Bezerra Menezesb ; Rodrigo V. Oliveirab ; Luiz Carlos P. Almeida Filhoa ; Jorge M. Martinsb ; Frederico B. Morenoc ; Ana Cristina O. Monteiro-Moreirac ; Arlindo A. Araripe Mourab ; Ana F. Urano Carvalhod ; aurano@ufc.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Comparative proteomics ; Detoxification ; Natural insecticide ; m-Pentadecadienyl-phenol
- 刊名：Acta Tropica
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：152
- 期：Complete
- 页码：49-55
- 全文大小：792 K
文摘
- •
The larvicidal activity of m-pentadecadienyl-phenol is based on the compound structure.
- •
Proteomic analysis of larvae of Aedes aegypti after exposure to m-pentadecadienyl phenol showed 12 spots differentially expressed.
- •
The natural insecticide caused elevated detoxification response.
- •
The insecticide caused overexpression of proteins that could indicate generation of reactive oxygen species and liberation of lysosomal content.
- •
Proteins overexpressed may lead to responses of apoptotic pathways.