- 作者：Zina Maria Almeida Azevedo ; Daniella Campelo Batalha Cox Moore ; Flavia Aparecida Alves de Matos ; Vania Matos Fonseca ; Maria Virginia Marques Peixoto ; Maria Ignez C. Gaspar-Elsas ; Erika Santinoni ; Luiz Antonio dos Anjos ; Eloane Gon?alves Ramos
- 关键词：Sepsis ; Electric impedance ; Child ; Multiple organ failure ; Critical illness
- 刊名：Clinical Nutrition
- 出版年：2013
- 出版时间：October, 2013
- 年：2013
- 卷：32
- 期：5
- 页码：824-829
- 全文大小：388 K
Summary
Background & aims
Currently, there are no clinical or laboratory parameters that can be used efficiently to predict the prognosis of critically ill patients, but in some situations, raw bioelectrical impedance parameters have been shown to be useful. The purpose of this study was to investigate the behavior of reactance and resistance in the severity of the critically ill pediatric patient.Methods
We prospectively analyzed bioelectrical impedance in a sample of 332 critically ill pediatric patients submitted to mechanical ventilation. The values taken on admission and discharge were correlated with major outcomes to the critically ill patient.
Results
We found an association of low values of Xc/H (<27.7?Ohm/m) and of R/H (<563.6?Ohm/m) on admission with multiple organs dysfunction greater or equal to 4. Both R/H and Xc/H increased significantly between admission and discharge among survivors, while among nonsurvivors there was a trend of decrease between admission and the last measurement before death.
Conclusions
Bioelectrical impedance is a useful tool for monitoring of critically ill pediatric patients. A possible role of R/H and Xc/H, especially the latter, as a predictive biomarker of evolution for septic shock and organ dysfunction still remains to be elucidated.