Metodolog¨ªa de presentaci¨®n de los resultados de progresi¨®n radiol¨®gica en estudios cl¨ªnicos
详细信息 查看全文
- 作者：Miriam Almirall Bernabé ; ; malmirall@imas.imim.es ; Joan Maymó ; Guasch ; Carolina Pé ; rez-Garcí ; a ; Marí ; a Pilar Lisbona Pé ; rez ; Jordi Carbonell Abelló
- 关键词：Artritis reumatoide ; Progresió ; n radiologica ; Diagramas de probabilidad acumulada
- 刊名：Seminarios de la Fundaci¨®n Espa?ola de Reumatolog¨ªa
- 出版年：2009
- 出版时间：March 2009
- 年：2009
- 卷：10
- 期：1
- 页码：2-7
- 全文大小：172 K
文摘
Recent clinical trials that evaluate treatment effectiveness in rheumatoid arthritis assess clinical response and progression of structural damage to joints by calculating radiographic progression over a given time period. In this article, we review three important features that have recently been developed in the methodology of scoring progression: presentation of radiographic data in clinical trials, following the preliminary guideline of van der Heijde, established in 2002, and additional new concepts such as estimated yearly progression rates and probability plots.