Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling
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- 作者：Kipyegon Kitur1 ; Sarah Wachtel2 ; Armand Brown2 ; Matthew Wickersham2 ; Franklin Paulino2 ; Herná ; n F. Peñ ; aloza3 ; Grace Soong2 ; Susan Bueno3 ; Dane Parker2 ; Alice Prince1 ; 2 ; asp7@columbia.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：23 August 2016
- 年：2016
- 卷：16
- 期：8
- 页码：2219-2230
- 全文大小：2299 K
文摘
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S. aureus activates RIPK1/RIPK3/MLKL-mediated necroptosis
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Mlkl−/− mice have increased inflammation and infection
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Necroptosis regulates inflammation in skin and systemic infection