Molecular cloning and expression of toll-like receptor 4 (tlr4) in the blunt snout bream (Megalobrama amblycephala)
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- 作者：Ruifang Laia ; lairuifang@webmail.hzau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Han Liua ; lifegood1986@126.com" class="auth_mail" title="E-mail the corresponding author ; Ivan Jakovlića ; ivanjakovlic@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Fanbin Zhana ; 1203248258@qq.com" class="auth_mail" title="E-mail the corresponding author ; Jin Weia ; 1161104243@qq.com" class="auth_mail" title="E-mail the corresponding author ; Pinhong Yangb ; yph098@163.com" class="auth_mail" title="E-mail the corresponding author ; Weimin Wanga ; wangwm@mail.hzau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Megalobrama amblycephala ; Fish ; tlr4 ; MyD88 ; Immunity ; Aeromonas hydrophila
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：59
- 期：Complete
- 页码：63-76
- 全文大小：6612 K
文摘
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Tlr4 gene was identified and characterised in Megalobrama amblycephala.
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Results indicate the importance of tlr4 in the development of the neural system.
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Both matlr4 and maMyD88 were up-regulation after A. hydrophila infection.
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Matlr4 plays a role in M. amblycephala immune response.