Ultrasound promoted aminolysis of epoxides in aqueous media: A rapid procedure with no pH adjustment for additive-free synthesis of β-aminoalcohols
详细信息 查看全文
- 作者：M. Saeed Abaee ; Vahid Hamidi ; Mohammad M. Mojtahedi
- 关键词：Aminolysis ; Ultrasound irradiation ; β ; -Aminoalcohols ; Aqueous media
- 刊名：Ultrasonics Sonochemistry
- 出版年：2008
- 出版时间：July 2008
- 年：2008
- 卷：15
- 期：5
- 页码：823-827
- 全文大小：143 K
文摘
An efficient and environmentally friendly procedure promoted by ultrasound irradiation is developed for stereoselective ring opening of various epoxides with aromatic and aliphatic amines under aqueous conditions in the presence of no catalyst or additive. Chemoselectivity of the protocol is shown by competition of piperidine and aniline to react with different epoxides resulting in exclusive formation of the respective products of piperidine.