Effect of garlic on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled clinical trials
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- 作者：Amirhossein Sahebkar ; Ph.D.a ; b ; Corina Serban ; Ph.D.c ; Sorin Ursoniu ; M.D. ; Ph.D.c ; Maciej Banach ; M.D. ; Ph.D. ; F.N.L.A. ; F.A.H.A. ; F.E.S.C. ; F.A.S.A.d ; Maciejbanach@aol.co.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：Lipoprotein(a) ; Garlic ; Allium sativum ; Lipids
- 刊名：Nutrition
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：32
- 期：1
- 页码：33-40
- 全文大小：1714 K
文摘
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Garlic can play an essential role in the prevention of atherosclerosis, but the research addressing the effect of garlic on the concentration of lipoprotein(a) [Lp(a)] has not been fully demonstrated.
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This meta-analysis of six available randomized controlled trials did not suggest a significant alteration in plasma Lp(a) levels after garlic consumption.
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When the studies were categorized according to the duration of supplementation, a significant elevation of plasma Lp(a) concentrations was found in trials lasting >12 wk.