A two-photon fluorescent probe for biological Cu (Ⅱ) and PPi detection in aqueous solution and in vivo

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• 作者：Mengmeng Guo^a ; ¹ ; Pengyu Dong^b ; ¹ ; Yan Feng^a ; Xinguo Xi^b ; Rong Shao^b ; Xiaohe Tian^c ; Buchang Zhang^d ; Manzhou Zhu^a ; Xiangming Meng^a ; ^{mengxm@ahu.edu.cn}
• 关键词：Two photon ; Fluorescent probe ; Pyrophosphate ; Tissue imaging ; In vivo imaging
• 刊名：Biosensors and Bioelectronics
• 出版年：2017
• 出版时间：15 April 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：276-282
• 全文大小：876 K
• 卷排序：90

文摘

The first two-photon fluorescent probe for Cu (II) /PPi in aqueous solution was developed. The probe exhibited large two-photon absorption cross sections at 740 nm. The probe can detect PPi released from DNA amplification after polymerase chain reactions. The probe was applied to image PPi in deep living tissues and zebrafish under TPM.