Structural basis for the regulation of nuclear import of Epstein-Barr virus nuclear antigen 1 (EBNA1) by phosphorylation of the nuclear localization signal
刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:26 February 2017
年:2017
卷:484
期:1
页码:113-117
全文大小:1875 K
卷排序:484
文摘
Nuclear import of EBNA1 can be regulated by phosphorylation of NLS. Crystal structures of importin-α1 bound to the NLS peptides of EBNA1 are solved. Structures provide insights into how phosphorylation can regulate nuclear import.