Analyses of polycyclic aromatic hydrocarbon (PAH) and chiral-PAH analogues-methyl-β-cyclodextrin guest-host inclusion complexes by fluorescence spectrophotometry and multivariate regression analysis

详细信息    查看全文

• 作者：LaVana Greene ; Brianda Elzey ; Mariah Franklin ; Sayo O. Fakayode ; ^{sofakayo@ncat.edu}
• 关键词：Guest-host-inclusion-complexation ; Cyclodextrin ; Polycyclic-aromatic-hydrocarbon ; Chemometrics-regression-analysis ; Fluorescence spectroscopy ; chiral analysis
• 刊名：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
• 出版年：2017
• 出版时间：5 March 2017
• 年：2017
• 卷：174
• 期：Complete
• 页码：316-325
• 全文大小：1411 K
• 卷排序：174

文摘

Guest-host inclusion complexation formation between polycyclic aromatic hydrocarbons anthracene and anthracene chiral derivatives (1-(9-anthryl)-2,2,2-triflouroethanol (TFE)) and methyl-β-cyclodextrin (Me-β-CD) was examined using fluorescence spectroscopy Me-β-CD shows enantiomeric and chiral discrimination of TFE enantiomers. Emission spectra data of anthracene-Me-β-CD and enantiomers of TFE-Me-β-CD-guest-host inclusion complexes was used subjected to chemometric partial-least-square (PLS) regression analysis The values of calculated binding constants and negative ΔG suggest the thermodynamic favorability of anthracene-Me-β-CD and enantiomeric of TFE-Me-β-CD inclusion complexation reactions. The PLS regression analysis resulted in square-correlation-coefficients of ≥ 0.997530 and a low LOD of 3.48 × 10− 8M and accurately determined the anthracene and TFE enantiomer concentrations with low error of ≤ 4.5%.