Decline of multidrug-resistant Gram negative infections with the routine use of a multiple decontamination regimen in ICU
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- 作者：Christophe Camusa ; b ; christophe.camus@chu-rennes.fr" class="auth_mail" title="E-mail the corresponding author ; Elise Sauvadeta ; Aude Tavenardb ; Caroline Piauc ; Fabrice Uhela ; b ; Pierre Boujua ; Julien Letheullea ; Gilles Dollod ; Arnaud Gacouina ; b ; Sylvain Lavoué ; a ; Yves Le Tulzoa ; b
- 关键词：Chlorhexidine ; Intensive care unit ; Multidrug-resistant Gram negative bacilli ; Mupirocin ; Selective digestive decontamination ; Topical antibiotics
- 刊名：Journal of Infection
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：73
- 期：3
- 页码：200-209
- 全文大小：515 K
文摘
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We assessed the long-term impact of decontamination on MDR AGNB acquired infections.
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AIs and colonization rates were prospectively recorded.
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The incidence rate of multidrug-resistant AGNB AIs substantially declined with time.
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ESBL-producing Enterobacteriaceae acquired rectal carriage also declined.
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Multiple decontamination did not favor the emergence of antimicrobial-resistant AGNB.