An Open-Label Phase II Randomized Trial of Topical Dexamethasone and Tacrolimus Solutions for the Treatment of Oral Chronic Graft-versus-Host Disease
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文摘

Intensive topical therapy with dexamethasone .5 mg/5 mL solution is effective for managing patients with new-onset symptomatic oral chronic graft-versus-host disease

The dexamethasone solution results support the most recent National Institutes of Health consensus ancillary care guidelines for management of oral chronic graft-versus-host disease

Topical tacrolimus .5 mg/5 mL solution is less effective than dexamethasone solution for managing patients with new-onset symptomatic oral chronic graft-versus-host disease; however, its relative efficacy and safety at higher concentrations are unknown

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