Cortical astrogliosis and increased perivascular aquaporin-4 in idiopathic intracranial hypertension
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- 作者：Per Kristian Eidea ; b ; p.k.eide@medisin.uio.no" class="auth_mail" title="E-mail the corresponding author ; peide@ous-hf.no" class="auth_mail" title="E-mail the corresponding author ; Vigdis Andersen Eidsvaaga ; c ; Erlend A. Nagelhusb ; c ; Hans-Arne Hanssond
- 关键词：AQP4 ; aquaporin-4 ; AU ; arbitrary units ; CSF ; cerebrospinal fluid ; GFAP ; glial fibrillary acidic protein ; ICP ; intracranial pressure ; IIH ; idiopathic intracranial hypertension ; ISF ; interstitial fluid ; IR ; immunoreactivity ; VRS ; Virchow-Robin paravascular space
- 刊名：Brain Research
- 出版年：2016
- 出版时间：1 August 2016
- 年：2016
- 卷：1644
- 期：Complete
- 页码：161-175
- 全文大小：5498 K
文摘
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Patchy astrogliosis is a prominent histopathological finding in IIH patients.
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Astrogliosis included cell hypertrophy, clustering of cells and loss of domains.
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AQP-4 immunoreactivity is increased over perivascular astrocytic endfeet.
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The degree of astrogliosis associated with perivascular AQP-4 immunoreactivity.