Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization

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• 作者：Rajendran Sribalan ; Vediappen Padmini ; ^{padimini_tamilenthi@yahoo.co.in" class="auth_mail" title="E-mail the corresponding author} ; ^{padmini.chem@mku.org" class="auth_mail" title="E-mail the corresponding author} ; Andiappan Lavanya ; Kandasamy Ponnuvel
• 关键词：Cholesterol ; Antimicrobial ; Glycinate ; Carbonate
• 刊名：Journal of the Saudi Pharmaceutical Society
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：24
• 期：6
• 页码：658-668
• 全文大小：1564 K

文摘

A series of glycinate and carbonate derivatives of cholesterol (4a–t) were synthesized, characterized and assessed for their in vitro antimicrobial activity. Our results revealed that the compounds exerted inhibitory activities against gram-negative bacteria and fungi.