TGF-¦Â Antagonists: Same Knot, but Different Hold

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• 作者：Andrew?P. Hinck ; Tao Huang
• 刊名：Structure
• 出版年：2013
• 出版时间：6 August, 2013
• 年：2013
• 卷：21
• 期：8
• 页码：1269-1270
• 全文大小：361 K

文摘

In this issue of Structure, Nolan and colleagues present the structure of BMP antagonist, PRDC, which adopts a head-to-tail dimer with distinct structure and inhibitory mechanism compared to other dimeric antagonists of the TGF-¦Â superfamily, such as noggin.